The occurrence of doxycycline residue in raw dairy milk from Malang and Padang Panjang, Indonesia

Abstract Antibiotic residue in milk has a negative impact on human health. The objective of this study was to determine the presence doxycycline residues fresh dairy and evaluate its dietary intake Indonesian population through consumption. Ninety samples were collected from District Malang (East Java Province) sixty-six Padang Panjang City (West Sumatera Province). All analyzed for using high-performance liquid chromatography (HPLC). estimated daily (EDI) determined by multiplying mean concentration antibiotics average consumption dividing it weight target. occurrence obtained raw 36.67% 12.12% Panjang. range 44.8-557.2 ng/g 203.0 14.2-64.5 30.1 Panjang, respectively. Samples shows highest EDI values both adult, children demonstrated toxicological risk together with present other types or groups foods. results show that, prevent effects antibiotic health, still needs be monitored regularly.